Nature Reviews Microbiology paper out
Target protection as a key antibiotic resistance mechanism https://www.nature.com/articles/s41579-020-0386-z
ToxSAS paper accepted to PNAS!
hope to share final version soon!
INTEGRATED STRUCTURAL BIOLOGY (ISB) POSTDOCTORAL PROGRAM PROJECT SUMMARY: Bacterial toxin-antitoxin (TA) systems have diverse functions, including defence against phages and maintenance of genetic elements. The lab of Gemma C. Atkinson has discovered a large network of promiscuous toxin-antitoxin domain pairs that swap partners across vast evolutionary distances. These novel TAs are being characterised microbiologically and…
Preprint out on characterisation of the yeast translation factor New1
Check it out on BioRxiv! A role for the Saccharomyces cerevisiae ABCF protein New1 during translation termination https://doi.org/10.1101/638064 This was another fun collaboration with the Hauryliuk and Wilson labs
Our ToxSAS toxin-antitoxin paper is on BioRxiv
Read all about our exciting discovery of a new toxin-antitoxin system here! https://www.biorxiv.org/content/10.1101/575399v2
Our Ribo-Seq analysis of eEF3 depleted yeast is out!
Atkinson lab paper on ABCFs accepted to JMB
Our ABCF paper available on BioRxiv here has been accepted to the Journal of Molecular Biology. It will appear in a special issue on antibiotic resistance in early 2019.
eEF3 ribosome profiling paper in bioRxiv
In this joint Hauryliuk/Johansson/Atkinson lab venture we aimed to establish the primary function of yeast eEF3: Elongation factor? Ribosome recycling factor? https://www.biorxiv.org/content/early/2018/09/10/413252
VmlR ABCF paper in PNAS
A great collaboration with the Wilson lab on the structure of ARE ABCF VmlR on the ribosome! http://www.pnas.org/content/early/2018/08/15/1808535115
The paper describing our bioinformatics tool FlaGs (Flanking Genes) is on BioRxiv!
FlaGs is a Python application for analysing conservation of gene neighbourhoods, and creating publication-quality figures. I’m very proud of my PhD student Chayan Kumar Saha for his heroic effort making this tool! Well done Chayan! The paper is here: https://www.biorxiv.org/content/early/2018/07/04/362095 And the tool itself is here: https://github.com/GCA-VH-lab/FlaGs Some example output: